Octozin – Treats sleeping sickness, Hole-in-the-Head, Malawi bloat, seawater Angel fish disease and Clown fish disease, marine whitespot, Spironucleus, Cryptobia, Bodomonas, Trypanoplasma & Trypanonosoma. Does not harm fish, plants or filters. For use in seawater, tropical freshwater and coldwater aquaria. Notes: Leave biological filtration running. Switch off u.v. sterilisers, ozonisers and remove zeolite & carbon before use. Replace 96 hours after 3rd dose. NB. Dissolve in a small amount of aquarium water, then pour into aquarium. Slight foaming may occur during use, this is harmless and soon disappears. Octozin is slow to biodegrade, therefore whilst not essential, you may effect a 50% water change on day 8. Do not use simultaneously with other medications. Allow at least 48 hours to elapse when changing treatment. Calculate aquarium capacity: For litres – (L x W x D) in cms divide by 1000. Allow for water displaced by rocks etc. Directions: 1 tablet treats 22.5 litre (5 lmp. Galls.). Frequency of Treatment: Use on days: 1,2 & 3. For marine whitespot, decrease S.G. to 1.017 for 2 to 3 weeks and use as stated above.